Toxicidad del imidacloprid en el desarrollo embrionario de roedores

Autores/as

Palabras clave:

Neonicotinoides, Efectos transgeneracionales, Exposición ambiental, Alteraciones metabólicas, Cambios reproductivos, Mamíferos

Resumen

Esta revisión tiene como objetivo comprender cómo el uso del neonicotinoide imidacloprid promueve efectos transgeneracionales en modelos animales. Aunque el IMI fue desarrollado y comercializado como seguro para los seres humanos debido a su especificidad por los receptores nicotínicos neuronales de los insectos, existen preocupaciones y evidencias sobre la exposición y los daños a organismos no objetivo. Nuestra hipótesis sugiere que la exposición embrionaria al IMI puede inducir alteraciones en la salud de los modelos animales experimentales durante la edad adulta y potencialmente transmitirse a generaciones posteriores. Los datos de la literatura indican que la exposición al IMI puede provocar efectos metabólicos, reproductivos, inmunológicos, conductuales y teratogénicos tanto en las generaciones parentales como en las descendientes. Esta revisión destaca los posibles riesgos para la salud asociados con la exposición a neonicotinoides, particularmente durante períodos críticos del desarrollo. Además, subraya la necesidad de métodos de evaluación estandarizados y regulaciones de seguridad para mitigar los riesgos de la exposición a neonicotinoides tanto para los seres humanos como para las especies no objetivo.

Biografía del autor/a

Bárbara Zanardini de Andrade, Universidade Estadual do Oeste do Paraná

Possui graduação em Ciências Biológicas (2016) e mestrado em Biociências e Saúde (2019) pela Universidade Estadual do Oeste do Paraná (UNIOESTE), onde atualmente curso doutorado no mesmo programa (desde 2022). Minha atuação concentra-se na linha de pesquisa "Fatores que Influenciam a Morfofisiologia Orgânica", com foco nos efeitos de intervenções como a exposição a xenobióticos sobre parâmetros metabólicos e morfológicos em modelos animais. Desenvolvi ampla experiência em consultoria de bioestatística, tanto de forma autônoma quanto no projeto de extensão "Qual é sua pergunta?" (UNIOESTE, desde 2019), aplicando técnicas de análise descritiva, inferencial e multivariada em projetos científicos de diferentes áreas.

Thaís Maylin Sobjak, Universidade Federal de Minas Gerais

Possui graduação em Ciencias Biologicas bacharelado pela Universidade Estadual do Oeste do Paraná(2013), graduação em Programa Especial de Formação de Docente pela Universidade Tecnológica Federal do Paraná(2017), especialização em Especialização em Análises clínicas e toxicológicas pelo Centro Universitário São Camilo(2020), especialização em MBA Gestão Ambiental e Desenvolvimento Sustentável pelo Centro de Ensino Superior de Maringá(2014) e mestrado em CONSERVAÇÃO E MANEJO DE RECURSOS NATURAIS pela Universidade Estadual do Oeste do Paraná(2016). Atualmente é Revisor de periódico da ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, Revisor de periódico da ECOLOGICAL INDICATORS e Doutoranda da Universidade Federal de Minas Gerais. Tem experiência na área de Bioquímica, com ênfase em Ecotoxicologia.

Leanna Camila Macarini, Universidade Federal do Paraná

Graduada em Ciências Biológicas Licenciatura e mestra em Conservação e Manejo de Recursos Naturais pela Universidade Estadual do Oeste do Paraná - UNIOESTE. Doutoranda em Ciências Biológicas Entomologia pela Universidade Federal do Paraná - UFPR. Ao longo da minha trajetória, me dediquei à pesquisa em qualidade ambiental e meu foco acadêmico se concentra no estudo de Comportamento Animal, Ecotoxicologia e Imunologia de insetos, com uma ênfase em grilos e abelhas. Atualmente, estou investigando os efeitos dos agrotóxicos sobre os sistemas antioxidantes de insetos, com o objetivo de compreender o estresse oxidativo celular em organismos não-alvo e os impactos ecológicos decorrentes dessa exposição.

Ana Tereza Bittencourt Guimarães, Universidade Federal de São Carlos

Possui graduação em Ciências Biológicas Bacharelado e Licenciatura pela Universidade Federal do Paraná (1998); mestrado em Ciências, área de concentração em Zoologia pela Universidade Federal do Paraná (2000); e doutorado em Ciências, área de concentração em Ecologia e Recursos Naturais pela Universidade Federal de São Carlos (2009). Pós-doutoranda no Programa de Gestão Ambiental da Universidade Positivo. Tem experiência na área de Bioestatística e Delineamento de Pesquisa, Ecologia Numérica e Ecotoxicologia. É consultora e assessora em Bioestatística, sócia administradora da Empresa Aquaflora e Meio Ambiente oferecendo serviços relacionados à conservação de ambientes naturais, de recursos hídricos e da biodiversidade, e por conseguinte, à saúde humana. Sócia fundadora da empresa "Qual é a sua Pergunta?" que oferece serviços de análises estatísticas na área de Ciências Biológicas e da Saúde. Atualmente, é professora da Associação Hospitalar de Proteção à Infância Dr. Raul Carneiro (Faculdade Pequeno Príncipe).

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Funding

This research was funded by the Brazilian Federal Agency for Support and Evaluation of Graduate Education (CAPES – Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) under grant number 88887.676039/2022-00.

Competing Interests

The authors declare no conflict of interest.

Author Contributions

Bárbara Zanardini de Andrade, Thaís Maylin Sobjak, Leanna Camila Macarini and Ana Tereza Bittencourt Guimarães contributed equally to this manuscript.

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2025-01-05

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Andrade, B. Z. de, Sobjak, T. M., Macarini, L. C., & Guimarães, A. T. B. (2025). Toxicidad del imidacloprid en el desarrollo embrionario de roedores. Revista Educação, Meio Ambiente E Saúde, 16, e-92. Recuperado a partir de https://www.remas.faculdadedofuturo.edu.br/remas/article/view/92

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Vol. 16 (2026)

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Derechos de autor 2026 Revista Educação, Meio Ambiente e Saúde

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